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Central Line-Related Bloodstream Infection by Saccharomyces cerevisiae Following Probiotic Use in a Patient with
1Department of Infectious Diseases, Kyung Hee University Hospital, Kyung Hee University College of Medicine, 23, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.
Abstract:
Clinical infections caused by Saccharomyces cerevisiae develop infrequently. We report a case of central line-related bloodstream infection caused by S. cerevisiae in a patient with Clostridioides difficile colitis and central venous catheter placement. The administration of probiotics in C. difficile colitis was associated with fungemia caused by S. cerevisiae. This case suggests the potential for serious infection caused by S. cerevisiae in immunocompromised patients with C. difficile colitis. Removal of the central venous catheter may be important for a better prognosis in fungemia caused by S. cerevisiae.
Insights
Saccharomyces cerevisiae infections are rare. This case highlights a central line-related bloodstream infection caused by S. cerevisiae in a patient with Clostridioides difficile colitis, suggesting a link with probiotic use.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Clinical Microbiology
Background:
- Clinical infections due to Saccharomyces cerevisiae are uncommon.
- Saccharomyces cerevisiae fungemia can occur, particularly in specific patient populations.
- Clostridioides difficile infection (CDI) is often associated with broad-spectrum antibiotic use and can predispose to other infections.
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