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The Pathogenesis, Clinical Features, and Treatment of Corynebacterium striatum-Related Infection

Huan Zhang1, Zheng Zhang1, Haiqing Shi1

  • 1Department of Critical Care Medicine, West China Hospital, Sichuan University, 37 Guo Xue Xiang Street, Chengdu 610041, China.

Microorganisms
|January 28, 2026
PubMed
Abstract

Insights

Corynebacterium striatum is a growing multidrug-resistant threat. This review details its pathogenesis, clinical features, and treatment, emphasizing site-specific variations for effective management.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Corynebacterium striatum (C. striatum) has emerged as a significant multidrug-resistant pathogen.
  • Its increasing virulence necessitates a comprehensive understanding of its clinical impact.

Purpose of the Study:

  • To review the pathogenesis, clinical characteristics, and treatment strategies for C. striatum infections.
  • To highlight recent advances in epidemiology and resistance mechanisms.

Main Methods:

  • Literature review focusing on epidemiology, virulence factors, resistance determinants, clinical manifestations, and treatment outcomes.
  • Synthesis of current knowledge on C. striatum infections.

Main Results:

  • C. striatum exhibits rapid evolution into a virulent, multidrug-resistant pathogen.
  • Therapeutic failures are common, leading to poor outcomes.
  • Clinical presentation and treatment efficacy vary significantly based on infection site.

Conclusions:

  • Recognizing site-specific clinical features and treatment strategies is crucial for managing C. striatum infections.
  • Further research is required to fully understand its clinical and genetic profiles.
Keywords:
Corynebacterium striatumclinical featuresmultidrug-resistantpathogenesistreatment

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