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Dietetic Prescriptions in Bipolar Disorder: Nutritional Strategies to Support Mood Stability and Reduce Relapse
Giuseppe Marano1,2, Ester Maria Marzo1,2, Greta Sfratta1,2
1Department of Neuroscience, Head-Neck and Chest, Section of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Life (Basel, Switzerland)
|January 28, 2026
Summary
Nutrition interventions show promise for managing bipolar disorder (BD). Dietary changes, including Mediterranean diets and specific nutrients, may improve mood and overall health, but more research is needed.
Area of Science:
- Nutritional Psychiatry
- Psychiatric Epidemiology
- Neurobiology
Background:
- Bipolar disorder (BD) is a chronic condition with significant functional impairment.
- Nutrition influences neurobiological pathways relevant to BD.
- Systematic dietary recommendations for BD are lacking.
Purpose of the Study:
- To review the role of nutrition in bipolar disorder.
- To identify potential dietary interventions for BD management.
- To highlight gaps in current nutritional research for BD.
Main Methods:
- Narrative review of literature from PubMed, Scopus, and Web of Science.
- Keywords: bipolar disorder, nutrition, dietary interventions, nutritional psychiatry.
- Synthesis of studies on nutritional patterns, components, and recommendations for BD.
Main Results:
- Nutritional interventions may impact mood, metabolic health, and treatment response in BD.
- Mediterranean diets, omega-3s, and micronutrients show potential benefits.
- Western diets may worsen mood instability and metabolic issues; research is heterogeneous.
Conclusions:
- Nutrition is a promising adjunctive strategy for bipolar disorder management.
- Dietary interventions can address psychiatric and physical health comorbidities.
- Further clinical trials are needed to establish evidence-based nutritional guidelines for BD.
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