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A 10-Year Study on Percutaneous Cholecystostomy for Acute Cholecystitis at a Tertiary Referral Hospital
Margarita Ptasnuka1,2,3, Ita Lazdane1, Vladimirs Fokins1,2
1Department of General and Emergency Surgery, Riga East Clinical University Hospital, LV-1038 Riga, Latvia.
Insights
Percutaneous cholecystostomy (PC) offers a safe and effective treatment for acute cholecystitis (AC) in high-risk patients. This minimally invasive procedure demonstrates low complication and mortality rates, serving as a viable alternative to surgery.
Area of Science:
- Medical procedures
- Gastroenterology
- Surgical interventions
Background:
- Acute cholecystitis (AC) poses significant risks for high-surgical-risk patients.
- Percutaneous cholecystostomy (PC) is a minimally invasive option for AC management.
- PC can serve as a bridge to definitive surgical treatment for critically ill patients.
Purpose of the Study:
- To evaluate the safety and efficacy of percutaneous cholecystostomy (PC) for acute cholecystitis (AC).
- To analyze complication rates, recurrence, and survival outcomes over a 10-year period.
- To identify risk factors associated with in-hospital mortality in patients undergoing PC for AC.
Main Methods:
- Retrospective analysis of 449 patients who underwent PC for AC between January 2013 and May 2023.
- Categorization into definitive treatment and bridging PC groups.
- Analysis of clinical characteristics, complications, recurrence, survival, and mortality risk factors.
Main Results:
- The majority of patients (89.5%) had an ASA score ≥ 3, indicating high surgical risk.
- Drainage tube-related complications occurred in 8.2% of patients; no procedure-related deaths were reported.
- Recurrent AC was observed in 7.6% of patients, with an overall mortality rate of 5.3%.
Conclusions:
- Percutaneous cholecystostomy (PC) is a safe and effective treatment for acute cholecystitis (AC) in high-risk populations.
- The procedure is associated with low complication and mortality rates.
- Sepsis on admission emerged as an independent risk factor for in-hospital mortality.
Abstract:
Background: Percutaneous cholecystostomy (PC) is an effective, minimally invasive treatment for patients with acute cholecystitis (AC) who are at high surgical risk and may be used as a bridge to surgery in critically ill patients. This study aimed to evaluate the safety of PC in patients with AC over a 10-year period. Methods: Patients who underwent PC for AC at our institution between January 2013 and May 2023 were included. Patients were categorised into the definitive and bridging PC groups. Clinical characteristics, procedure-related complications, recurrence, and overall survival were analysed. Statistical analyses were used to identify in-hospital mortality-related risk factors. Results: A total of 449 patients were included, and 89.5% had an ASA score ≥ 3. The median time to PC was 1 day, and 17.6% of patients required ICU admission. Drainage tube-related complications occurred in 37 (8.2%) patients. The median drainage and hospital stay durations were 9 (IQR 6-14) and 12 (IQR 9-15) days, respectively. During follow-up, recurrent AC was observed in 34 (7.6%), with a median time to recurrence of 63 (IQR 29-312) days. PC was the definitive treatment in 275 (61.2%) patients. The overall mortality rate was 5.3% (n = 24), with no deaths related to the drainage procedure. Sepsis on admission was an independent risk factor related to in-hospital mortality. Conclusions: Our findings confirmed that PC is a safe and effective treatment alternative for managing AC in high-risk patients with low complication and mortality rates.
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