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Updated: Jan 29, 2026

A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique
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Accelerating the Adoption of Best Practice Research in Resuscitation Through Implementation Science: Identifying Gaps

Shohreh Majd1,2, Sze Ling Chan3,4, Mojca Bizjak-Mikic1

  • 1Council of Ambulance Authorities, Hilton, SA 5033, Australia.

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|January 28, 2026
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Summary

Implementing evidence-based resuscitation is slow, impacting patient outcomes. This study uses the Knowledge-to-Action framework to address barriers and improve adoption of practices like dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) for better survival rates.

Keywords:
healthcare deliveryimplementation scienceknowledge-to-actionpatient outcomesresuscitation

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Area of Science:

  • Implementation Science
  • Resuscitation Medicine
  • Healthcare Systems Research

Background:

  • Translating evidence-based resuscitation practices into clinical settings is slow and inconsistent.
  • This gap significantly impacts patient survival and neurological outcomes.
  • Implementation science provides structured approaches to accelerate adoption by identifying and overcoming context-specific barriers.

Purpose of the Study:

  • To apply the Knowledge-to-Action (KTA) framework to resuscitation practices.
  • To provide guidance for implementing evidence-based resuscitation in various settings (DA-CPR, in-hospital, EMS).
  • To introduce a comprehensive outcomes framework and practical tools for sustainable integration.

Main Methods:

  • Application of the Knowledge-to-Action (KTA) framework.
  • Emphasis on stakeholder engagement, iterative monitoring, and sustainability.
  • Development of a comprehensive outcomes framework and decision-oriented pilot testing table.

Main Results:

  • Detailed guidance is provided for dispatch-assisted cardiopulmonary resuscitation (DA-CPR), in-hospital code teams, and emergency medical services (EMS).
  • A comprehensive outcomes framework is introduced, covering implementation, service/system, and patient-level metrics.
  • Case examples illustrate practical applications, including DA-CPR and real-time feedback devices.

Conclusions:

  • The KTA framework offers a structured approach to accelerate the adoption of evidence-based resuscitation.
  • Tailored strategies addressing barriers like dispatcher workload and resource constraints are crucial.
  • Sustainable integration of resuscitation protocols is achievable through guided implementation and comprehensive outcome monitoring.