Clinical Outcomes of Intra-Articular Ozone Injections in Hip Osteoarthritis: A Retrospective Study Comparing...

Area of Science:

• Orthopedics
• Regenerative Medicine
• Pain Management

Background:

• Hip osteoarthritis (OA) is a debilitating condition with limited treatment options.
• Intra-articular injections are a common therapeutic approach for OA.
• Ozone therapy is an emerging treatment modality for various musculoskeletal conditions.

Purpose of the Study:

• To evaluate the association between the number of intra-articular ozone injection sessions and clinical outcomes in patients with hip OA.
• To determine if a higher number of ozone sessions correlates with improved pain reduction and functional status.
• To assess the safety and efficacy of intra-articular ozone injections for hip OA.

Main Methods:

• Retrospective analysis of 54 patients (65 hips) with Tönnis grade 1-2 hip OA.
• Patients received 1, 2, or 3 intra-articular ozone injection sessions.
• Pain and function assessed using Visual Analog Scale (VAS) and Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index at multiple follow-up points.

Main Results:

• All treatment groups showed significant improvements in VAS and WOMAC scores compared to baseline (p < 0.001).
• The three-session group exhibited numerically greater improvements in pain and function at early and late follow-ups.
• Intergroup differences in outcomes did not consistently reach statistical significance.

Conclusions:

• Intra-articular ozone injections are associated with positive clinical outcomes in hip OA patients.
• A three-session ozone regimen may lead to more pronounced pain relief and functional recovery.
• Further randomized controlled trials are needed to confirm these findings and establish optimal treatment protocols.