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Updated: Jan 29, 2026

Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
Prevalence of Positive Screening of Sleep-Disordered Breathing Among Children and Adolescents in Orthodontic
Maurizio Ledda1, Chiara Pili1, Silvia Mura1
1Department of Surgical Sciences, Postgraduate School in Orthodontics, University of Cagliari, 09124 Cagliari, Italy.
Insights
Pediatric orthodontic patients show a high prevalence of sleep-disordered breathing (SDB) risk, indicating a need for routine screening. Early identification is crucial for children
Area of Science:
- Pediatric dentistry
- Sleep medicine
- Orthodontics
Background:
- Sleep-disordered breathing (SDB) is linked to craniofacial development and orthodontic issues in children.
- Early SDB risk detection in orthodontic patients is vital but lacks comprehensive evidence.
Purpose of the Study:
- To systematically review the prevalence of high SDB risk in pediatric orthodontic patients.
- To summarize findings from studies utilizing validated screening questionnaires for SDB risk.
Main Methods:
- Systematic literature search across major databases (PubMed, Scopus, etc.) following PRISMA guidelines.
- Inclusion of cross-sectional studies on children undergoing orthodontic treatment using validated SDB questionnaires (e.g., PSQ, OSA-18).
- Assessment of study quality using JBI Critical Appraisal Checklist and evidence certainty with GRADE approach.
Main Results:
- Twelve studies (3737 participants, 2011-2025) reported high SDB risk prevalence ranging from 1.2% to 69%.
- Higher prevalence observed in children with malocclusions, oral breathing, or craniofacial risk markers.
- Included studies generally had moderate quality, utilizing validated screening tools.
Conclusions:
- Pediatric orthodontic populations exhibit a significant prevalence of high SDB risk.
- Orthodontists should integrate validated SDB risk questionnaires into routine screenings.
- Further research is needed to address methodological limitations and explore causal links between craniofacial development and SDB.
Abstract:
Background/Objectives: Sleep-Disordered Breathing (SDB) in children is closely associated with craniofacial growth and orthodontic conditions. Early identification of SDB risk in orthodontic populations is crucial, yet evidence remains fragmented. This systematic review aimed to summarize the prevalence of high SDB risk in pediatric orthodontic patients assessed through validated questionnaires. Methods: A systematic search was conducted across PubMed, Scopus, Web of Science, Cochrane Library and Embase following PRISMA guidelines. Inclusion criteria comprised analytical cross-sectional studies assessing SDB risk in children undergoing or seeking orthodontic treatment, using validated questionnaires such as the Pediatric Sleep Questionnaire (PSQ), OSA-18, or Sleep Clinical Record (SCR). The methodological quality of the included studies was assessed using the "JBI Critical Appraisal Checklist for Studies Reporting Prevalence Data". The certainty of the evidence was additionally evaluated using the GRADE approach. Results: Twelve studies published between 2011 and 2025 met the inclusion criteria, totaling 3737 participants. Across studies, the mean prevalence of high SDB risk ranged from a minimum of 1.2% to a maximum of 69%, with consistently higher values in populations exhibiting malocclusions, oral breathing patterns, or craniofacial risk markers. All studies clearly described their populations and used validated screening tools, resulting in moderate overall quality. Conclusions: Pediatric orthodontic populations demonstrate a substantial prevalence of high SDB risk, suggesting that orthodontists should systematically incorporate validated questionnaires into routine screening. The evidence base, although consistent, remains limited by methodological weaknesses. Further well-designed studies are needed to clarify causal relationships between craniofacial development and SDB.
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