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Variability in Post-Discharge Mortality Rates and Predictors over Time: Data from a Five-Year Ward-Wide Study
Giuseppe A Ramirez1,2, Bruno N Germinario3, Giovanni Benanti1,3
1Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS Ospedale San Raffaele, via Olgettina 60, 20132 Milan, Italy.
Over half of patients hospitalized for complex chronic conditions died within five years. Identifying predictors of mortality can improve care and palliative referrals for these vulnerable individuals.
Area of Science:
- Gerontology
- Internal Medicine
- Public Health
Background:
- Complex chronic disorders are increasing, leading to frequent hospitalizations.
- Long-term post-discharge mortality and its predictors in these patients are poorly understood.
- This knowledge gap may result in suboptimal care and delayed palliative care referrals.
Purpose of the Study:
- To evaluate the five-year post-discharge mortality rates.
- To identify predictors of mortality in elderly, multi-morbid patients admitted to Internal Medicine.
- To inform patient management and palliative care integration.
Main Methods:
- Analysis of a cohort of elderly, multi-morbid patients admitted to Internal Medicine over 12 months.
- Utilized public health registries to track five-year mortality (up to 2022) for discharged patients.
- Examined clinical factors, frailty, care intensity, and patient complexity as predictors.
Main Results:
- Five-year post-discharge mortality reached 57%, with a 32% one-year peak.
- Cancer, neurological, liver, and respiratory disorders predicted early/intermediate mortality.
- Renal disorders, dependence, and immunodepression predicted first-year mortality.
- Cardiovascular and GI disorders predicted late mortality.
- Frailty and care complexity predicted mortality across all timeframes.
Conclusions:
- A significant proportion of Internal Medicine patients may benefit from palliative care.
- Understanding differential mortality predictors aids patient management.
- Early or simultaneous palliative care identification is crucial for at-risk individuals.
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