Related Experiment Video
Updated: Jan 29, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
Good Dietary Control Significantly Improves Anthropometric and Metabolic Parameters and Liver Function in Patients
Bogusława Luzak1, Patrycja Szymańska1,2, Marcin Kosmalski3
1Department of Hemostasis and Hemostatic Disorders, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland.
None:
Background/Objectives: The aim of the study was to analyze dietary and lifestyle adherence in patients with type 2 diabetes mellitus (T2DM) under the care of a diabetes clinic. Methods: The study included two groups: patients under the close control of a dietitian (n = 50) who followed a standard (DD) or fiber-enriched diabetic diet (FD), and patients under the care of a diabetes clinic without close supervision of a dietitian (n = 50). Results: After 3 months, both DD and FD significantly improved metabolic control in the patients under the care of a dietitian. However, FD was slightly better compared to DD (BMI reduction by an average of 2.4% (95% CI: 1.6%; 3.1%) for DD vs. 4.8% (95% CI: 3.6%; 6.0%) for FD; waist circumference decreasing 2.0% (95% CI: 1.2%; 3.4%) for DD vs. 3.5% (95% CI: 2.6%; 4.3%) for FD, p < 0.01; glycemia reduction 19.9% (95% CI: 14.8%; 25.0%) for FD vs. 5.6% (95% CI: 1.9%; 9.3%) for DD, p < 0.001; GGTP activity reduction 35.7% (95% CI: 28.9%; 42.5%) for FD vs. 1.8% (95% CI: -15.2%; 18.3%) for DD, p < 0.001). In addition, only half of the patients without the close supervision of a dietitian declared adherence to the diet. Most respondents had a satisfactory level of nutritional knowledge, but the analysis indicates the weakly marked influence of the protective features of nutrition as well as evidence of the low contribution of an unhealthy diet. Conclusions: Considering the level of nutritional knowledge and low awareness of their health condition in many patients, visits to the doctor and brief nutrition education are not enough for dietary care in T2DM patients. A dietitian's care is necessary to improve their health.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Types of Functions I
Types of Functions II
Pharmacokinetics in Pediatric Patients: Drug Metabolism

