Clinical Burden and Healthcare Utilization Associated with Hospitalizations of RSV-Infected Polish Children During

Jan Mazela1,2, Teresa Jackowska3, Marcin Czech4

  • 1Department of Neonatology, Poznan University of Medical Sciences in Poznan, 60-535 Poznań, Poland.

Viruses
|January 28, 2026
PubMed

Insights

Severe respiratory syncytial virus (RSV) primarily affects infants without comorbidities. Preventive strategies for RSV should be broadly applied to all children, not just those in high-risk groups, to reduce disease burden.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Respiratory syncytial virus (RSV) is a major cause of severe respiratory illness and hospitalization in young children globally.
  • Characterizing RSV hospitalizations in Poland is crucial for understanding disease burden and informing public health strategies.

Purpose of the Study:

  • To analyze the clinical and epidemiological features of children under five hospitalized with RSV in Poland.
  • To describe current treatment patterns for RSV infections in hospitalized pediatric patients.

Main Methods:

  • Retrospective observational study conducted across 41 Polish hospitals from November 2023 to February 2024.
  • Data collected from 419 pediatric patients (age ≤5 years) with confirmed RSV infection (antigen test or RT-PCR).
  • Weighted and extrapolated data to represent the national population of hospitalized RSV patients aged 0-5 years.

Main Results:

  • The majority of hospitalized patients (57.4%) were infants under 12 months; 85.8% had no comorbidities.
  • Pneumonia (56.8%), bronchiolitis (35.9%), and bronchitis (12.4%) were the most common RSV manifestations.
  • Treatments included respiratory support (21.1%), inhaled steroids (67.6%), antibiotics (61.5%), beta2-mimetics/anticholinergics (48.1%), and systemic steroids (44.3%).

Conclusions:

  • Severe RSV predominantly impacts young children without pre-existing health conditions.
  • Current treatment patterns involve significant use of respiratory support and various therapies, including steroids and antibiotics.
  • Broadening preventive strategies beyond high-risk groups is recommended to decrease the overall burden of RSV disease.
Abstract

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