Related Experiment Video
Updated: Jan 29, 2026

Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection
Published on: May 2, 2011
Navigating Vaccines with Confidence: Assessing Current and Past Community-Based Vaccination Efforts in Rural Eastern
Sarah B Maness1, Alice R Richman2, Abby J Schwartz2
1Department of Health Education and Promotion, College of Health and Human Performance, East Carolina University, 300 Curry Court, Greenville, NC 27858, USA.
Community-based vaccination programs in rural North Carolina face challenges with hesitancy and access. Enhancing trust, education, and engagement through tailored strategies is key to increasing vaccine uptake in these underserved populations.
Area of Science:
- Public Health
- Health Communication
- Vaccinology
Background:
- Vaccination is critical for community infectious disease control, yet vaccine hesitancy and declining uptake pose significant public health challenges.
- Rural communities, particularly in Eastern North Carolina, face unique barriers to vaccine access and confidence due to limited resources.
- Understanding existing community-based vaccination efforts is crucial for developing effective strategies to improve vaccine uptake.
Purpose of the Study:
- To describe the current landscape of community-based vaccination initiatives in rural Eastern North Carolina.
- To identify key components of successful community-based vaccination programs.
- To assess the feasibility and community support for a new vaccine education and navigation program.
Main Methods:
- Conducted 25 semi-structured qualitative interviews with individuals involved in vaccination education and navigation programs.
- Participants were managers or coordinators from health agencies, clinics, and pharmacies in three rural Eastern North Carolina counties.
- Interview data were transcribed, coded using NVivo, and analyzed thematically to identify insights and themes.
Main Results:
- Strengths of current efforts include patient education, inter-organizational partnerships, and community engagement via social media, flyers, and trusted leaders.
- Areas for improvement involve broader audience engagement, building vaccine trust, and expanding education for hard-to-reach populations.
- Participants supported a proposed education and navigation program, citing potential for overcoming hesitancy with incentives and trusted messengers.
Conclusions:
- A significant need exists for enhanced trust-building, education, and patient engagement in rural Eastern North Carolina's vaccination efforts, especially for vulnerable groups.
- The study confirmed the feasibility and community support for an integrated vaccine education and navigation program.
- An integrated program was developed and implemented based on study findings to address identified gaps and improve vaccine uptake.
Related Concept Videos
Vaccinations
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Confidence Coefficient
What are Populations and Communities?
Confidence Intervals
A...

