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Integrin alpha L: structure, cellular functions, and emerging role in human diseases

Xianglin Wang1,2, Guoya Yang1, Yanpei Chen1

  • 1The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, China.

Frontiers in Immunology
|January 28, 2026
PubMed
Summary

Integrin α L, a key part of LFA-1, is vital for immune cell movement and interactions. This review explores its roles in cancer and other diseases, highlighting its potential as a diagnostic biomarker and therapeutic target.

Keywords:
Integrin α Lbiomarkercancerhuman diseaseimmune regulationintercellular adhesion molecule

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