Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

361
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
361
X-ray Imaging01:24

X-ray Imaging

10.1K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
10.1K
Brain Imaging01:14

Brain Imaging

727
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
727
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

271
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
271
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

9.3K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
9.3K
Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

429
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
429

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

New insights in tumor-on-a-chip models for studying cancer drug resistance.

Pathology, research and practice·2026
Same author

Low-FREquency Deep TRanscranial Magnetic Stimulation in ACute Ischaemic StrokE within 48 Hours (RETRACE-I): rationale and design of a randomised, multicentre, open-label, blinded endpoint trial.

Stroke and vascular neurology·2026
Same author

Engineering a robust IsPETase for energy-efficient PET depolymerization in natural seawater at ambient temperatures.

Advanced biotechnology·2026
Same author

Lesion network mapping navigated continuous theta burst stimulation for motor recovery in acute ischaemic stroke (MASTRE): rationale and design of a randomised double-blind controlled multicentre phase 2 trial.

Stroke and vascular neurology·2026
Same author

Vertical distribution of antimicrobial resistance genes in soil adjacent to contaminated sites with animal manure.

Environmental geochemistry and health·2026
Same author

Glycine max Jumonji C domain-containing proteins JMJ19/20 exhibit endopeptidase activity and interact with LUXs to mediate flowering time.

Nucleic acids research·2026

Related Experiment Video

Updated: Jan 29, 2026

In vivo Near Infrared Fluorescence NIRF Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis
09:43

In vivo Near Infrared Fluorescence NIRF Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis

Published on: August 4, 2011

18.5K

Multimodal imaging for early drusen detection: RM-SLO as a promising imaging approach.

Shujun Zhang1, Xiaoling Zhang1, Zixun Wang2

  • 1Handan Eye Hospital (The Third Hospital of Handan), Hebei, China.

Frontiers in Medicine
|January 28, 2026
PubMed
Summary

Retro-mode scanning laser ophthalmoscopy (RM-SLO) significantly outperforms other imaging methods in detecting drusen, offering superior clarity for early age-related macular degeneration (AMD) diagnosis. This advanced technique aids in identifying small lesions crucial for timely clinical management.

Keywords:
age-related macular degenerationdrusenearly detectionmultimodal imagingretro-mode scanning laser ophthalmoscopy

More Related Videos

4D Multimodality Imaging of Citrobacter rodentium Infections in Mice
12:38

4D Multimodality Imaging of Citrobacter rodentium Infections in Mice

Published on: August 13, 2013

13.5K
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.2K

Related Experiment Videos

Last Updated: Jan 29, 2026

In vivo Near Infrared Fluorescence NIRF Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis
09:43

In vivo Near Infrared Fluorescence NIRF Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis

Published on: August 4, 2011

18.5K
4D Multimodality Imaging of Citrobacter rodentium Infections in Mice
12:38

4D Multimodality Imaging of Citrobacter rodentium Infections in Mice

Published on: August 13, 2013

13.5K
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.2K

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Diseases

Background:

  • Age-related macular degeneration (AMD) is a leading cause of vision loss.
  • Early detection of drusen is crucial for managing AMD.
  • Conventional imaging techniques have limitations in detecting subtle drusen.

Purpose of the Study:

  • To evaluate the diagnostic performance of retro-mode scanning laser ophthalmoscopy (RM-SLO) for drusen detection.
  • To compare RM-SLO with conventional multimodal imaging techniques.
  • To explore RM-SLO's imaging characteristics for early AMD.

Main Methods:

  • A cross-sectional study involving 192 patients (263 eyes).
  • Imaging modalities included color fundus photography (CFP), optical coherence tomography (OCT), fundus fluorescein angiography (FFA), fundus autofluorescence (FAF), and RM-SLO.
  • Retinal specialists independently assessed images for drusen; detection rates were compared statistically.

Main Results:

  • RM-SLO detected drusen in 38.78% of eyes, significantly higher than OCT (22.05%), CFP (8.37%), FFA (5.32%), and FAF (4.18%).
  • RM-SLO provided clear pseudo-three-dimensional visualization, identifying both hard and soft drusen, including small lesions missed by other methods.
  • OCT showed higher detection rates than CFP, FAF, and FFA.

Conclusions:

  • RM-SLO exhibits superior sensitivity and imaging clarity for drusen detection compared to conventional multimodal imaging.
  • RM-SLO's ability to visualize small, distinct drusen makes it a promising tool for early AMD screening.
  • This technique can enhance clinical management of patients with early AMD.