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Tear proteomic analysis in keratoconus patients and potential biomarkers: a case-control study

Daniel de Almeida Borges1, Marcos Rodrigo Alborghetti2, Romenia Ramos Domingues2

  • 1Department of Ophthalmology and Otorhinolaryngology, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.

Experimental Biology and Medicine (Maywood, N.J.)
|January 28, 2026
PubMed
Summary

Researchers identified 37 differing proteins in the tear film of keratoconus patients, including 7 overlapping biomarkers. This proteomic analysis offers insights into keratoconus pathophysiology and potential diagnostic markers.

Keywords:
biomarkerscorneakeratoconusproteomicstear film

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