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Updated: Jan 29, 2026

Characterizing Extracellular Vesicles from Biological Fluids
Published on: February 28, 2025
Small equatorial deformation of homogeneous spherical fluid vesicles
Andrés Solís-Cuevas1, Pablo Vázquez-Montejo2
1Facultad de Matemáticas, Universidad Autónoma de Yucatán, Periférico Norte, Tablaje 13615, 97110, Merida, Yucatán, Mexico.
Abstract:
We examine the reaction of a homogeneous spherical fluid vesicle to the force exerted by a rigid circular ring located at its equator in the linear regime. We solve analytically the linearized first integral of the Euler-Lagrange equation subject to the global constraints of fixed area and volume, as well as to the local constraint imposed by the ring. We determine the first-order perturbations to the generating curve of the spherical membrane, which are characterized by the difference of the radii of the membrane and the ring, and by a parameter depending on the physical quantities of the membrane. We determine the total force that is required to begin the deformation of the membrane, which gives rise to a discontinuity in the curvature of the membrane across the ring.
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