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Integral Approach in the Follow-up of Prostate Cancer Patients: SOGUG Multidisciplinary Expert Panel Insights
María José Méndez-Vidal1, Enrique Gallardo2, Alfonso Gómez de Iturriaga3
1Maimonides Institute for Biomedical Research of Córdoba (IMIBIC), Reina Sofía University Hospital (HURS), Department of Medical Oncology, Córdoba, Spain.
Clinical Genitourinary Cancer
|January 28, 2026
Summary
Prostate cancer (PCa) management is improving with new treatments like genetic biomarkers and PARP inhibitors. Optimizing treatment sequencing and multidisciplinary care is key to improving outcomes for aggressive PCa cases.
Area of Science:
- Oncology
- Urology
- Medical Genetics
Background:
- Prostate cancer (PCa) is a globally prevalent malignancy in men, characterized by significant heterogeneity.
- While many PCa cases are indolent, aggressive forms can lead to metastasis and poor prognosis, particularly castration-resistant metastatic disease.
Purpose of the Study:
- To summarize current challenges and expert insights in optimizing prostate cancer management.
- To highlight advancements in diagnosis, treatment, and monitoring strategies for PCa patients across various risk groups and stages.
Main Methods:
- Expert panel review and summarization of current therapeutic options and challenges.
- Analysis of advancements in genetic biomarkers, imaging, targeted therapies (e.g., AR signaling inhibitors, PARP inhibitors), chemotherapy, and radiopharmaceuticals.
Main Results:
- Significant improvements in PCa diagnosis and treatment are driven by novel biomarkers, imaging, and targeted therapies.
- New therapeutic options complement standard treatments like radiation and surgery, but optimal sequencing is crucial.
Conclusions:
- Understanding current therapeutic options and their sequencing is vital for improving PCa treatment outcomes.
- Multidisciplinary team decision-making, patient journey comprehension, and addressing unmet needs are essential for real-world PCa management and quality of life.
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