Related Experiment Video
Updated: Jan 30, 2026

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
Published on: September 5, 2011
Perinatal Outcome of Early- and Late-Onset Selective Fetal Growth Restriction in Monochorionic Diamniotic Twin
Li Zhao1, Yan-Hua Zhang1, Lu Chen1
1The Women's Hospital School of Medicine Zhejiang University, Hangzhou, China.
Objective:
To compare clinical differences and growth velocity patterns between early- and late-onset selective fetal growth restriction (sFGR) in monochorionic diamniotic (MC) twins.
Methods:
A retrospective cohort study analyzed 394 MC twin pregnancies with sFGR (2017-2024). Early-onset (≤ 24 weeks) and late-onset (> 24 weeks) groups were compared for fetal growth velocity (serial EFW measurements) and perinatal outcomes (composite morbidity/mortality).
Results:
Before 28 weeks, the larger twin's EFW growth was similar in both groups. The smaller twin in late-onset sFGR grew faster than in early-onset sFGR until 32.9 weeks. Early-onset sFGR is associated with higher rates of Type II/III sFGR (31.7% vs. 9.8% in late-onset). Perinatal mortality was similar (5.8% vs. 4.7%), but adverse outcomes were higher in early-onset (69.5% vs. 48.6%). Median delivery GA was earlier in early-onset (32.7 vs. 34.3 weeks).
Conclusions:
In MCDA twin pregnancies, early-onset sFGR leads to more adverse perinatal outcomes than late-onset cases, despite similar perinatal mortality rates. Early-onset sFGR is more often associated with Type II and III sFGR. This information can help clinicians offer better counseling on perinatal outcomes and management strategies.
More Related Videos
09:52Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
Published on: September 5, 2011
09:51Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
Published on: March 21, 2018
Related Concept Videos
Restriction Enzymes
The host bacteria protect their own genomic DNA from these enzymes by methylating these sites. Some...
Predicting Reaction Outcomes
Outcomes of Glycolysis
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Fetal Circulation
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Guidelines for Writing Outcome
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
What is Natural Selection?