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Adherence to oral endocrine therapy by menopausal status: post hoc insights from a remote monitoring randomized trial
Ilana Graetz1,2, Xin Hu3,4, Rebecca A Krukowski5
1Rollins School of Public Health, Emory University, Atlanta, GA, USA. ilana.graetz@emory.edu.
Abstract:
Oral adjuvant endocrine therapy (AET) improves survival in hormone receptor-positive breast cancer, but younger, premenopausal women often struggle with adherence. In a post hoc analysis of a randomized trial (N = 304), app-based remote symptom monitoring improved 12-month AET adherence among premenopausal women (App-only: 53.9% vs. EUC: 25.0%), with no benefit for postmenopausal women. Findings suggest remote monitoring may help close adherence gaps in younger patients. Prospectively registered on ClinicalTrials.gov: NCT03592771.
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