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Artificial Intelligence-Based Multi-Stage System for Automated Angle's Classification of Malocclusion from Intraoral
Shahab Kavousinejad1, Sara Ghazanfari2, Sara Alsadat Hosseinikhah Manshadi3
1Dentofacial Deformities Research Center, Research Institute of Dental Sciences, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran. dr.shahab.k93@gmail.com.
Journal of Imaging Informatics in Medicine
|January 28, 2026
Summary
This study introduces a deep learning pipeline for automated Angle
Area of Science:
- Dentistry
- Artificial Intelligence
- Medical Imaging
Background:
- Accurate Angle's classification of occlusion is crucial in orthodontics.
- Manual classification is time-consuming and prone to variability.
Purpose of the Study:
- To develop and validate a multi-stage deep learning pipeline for automated Angle's classification of occlusion using intraoral images.
- To assess the pipeline's accuracy, speed, and clinical applicability.
Main Methods:
- A pipeline integrating Occlusion Side Classification (OSC), side-specific MolarBBoxNet, and AngleClassifier-R50 was developed.
- Trained on 8909 intraoral occlusion images, validated on 383 unseen images.
- Grad-CAM visualizations were used for interpretability.
Main Results:
- Perfect occlusion side classification (accuracy 1.00) and high molar classification accuracy (97.41% internal, 94.3% external).
- High accuracy for Class I (99.0% sensitivity, 98.9% specificity), Class II (88.2% sensitivity, 98.7% specificity), and Class III (97.2% sensitivity, 93.4% specificity).
- Processing time of ~0.11s per image, significantly faster than manual annotation.
Conclusions:
- The deep learning pipeline accurately and efficiently classifies Angle's occlusion from intraoral images.
- The system demonstrates potential for general practice, tele-orthodontics, large-scale screening, and reducing diagnostic variability.
- Future work may involve multimodal inputs for comprehensive orthodontic diagnostics.
Keywords:
Artificial intelligenceComputer visionDeep learningMalocclusion, Angle’s classificationOrthodontics
