Related Experiment Video
Updated: Jul 11, 2026

A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus
Published on: March 28, 2017
Staphylococcus aureus's golden-yellow pigment staphyloxanthin: production enhancement, analytical characterization,
Ahmed M Nosair1, Amal M Abo-Kamar2, Lamiaa A Al-Madboly2
1Department of Microbiology and Immunology, Faculty of Pharmacy, Tanta University, Tanta, Egypt. ahmed.nosir@pharm.tanta.edu.eg.
Abstract:
Staphyloxanthin (STX), an apocarotenoid golden yellow pigment produced by Staphylococcus aureus isolates, is endowed with potent antioxidant capacity. It plays a crucial role in combating reactive oxygen species (ROS), exhibiting considerable application prospects. This review provides a comprehensive overview of the biosynthetic pathway and various approaches for STX bioproduction in S. aureus. Moreover, this review focuses on advancements in biotechnology for enhancing the yield of STX in S. aureus, including mutagenesis breeding, metabolic engineering, transcriptional regulation, and the optimization of fermentation conditions. This review addresses the extraction process, purification, and analytical characterization of STX pigment. Additionally, this review highlights the diverse applications of STX in healthcare settings as an antibacterial, antifungal, antiparasitic, antioxidant, anticancer, and DNA damage protection agent. To the best of our knowledge, this is the first review reporting the biotechnological aspects of STX from S. aureus as a natural biotechnologically valued product.
More Related Videos
Related Concept Videos
Fixation and Sectioning
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
Special Staining Techniques
Staphylococcal Skin Infections
Clinical Significance of Antibiotic Resistance

