Related Experiment Video
Updated: Jan 30, 2026

Author Spotlight: Understanding the Effect of Herbal-Cake-Separated Moxibustion in Rats with Renal Faliure
Published on: December 22, 2023
Correlation between life satisfaction, pleasure level, and negative emotion in patients with chronic renal failure
Lin-Lin Zhang1, You-Li Zhang2, Ting Liu3
1Department of Respiratory Intensive Care Unit, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, Liaoning Province, China.
Background:
Anxiety, depression, and other negative emotions are common among patients with chronic renal failure (CRF). Analyzing the factors related to negative emotions is necessary to provide targeted nursing care.
Aim:
To explore the correlations among life satisfaction, pleasure levels, and negative emotions in patients with CRF.
Methods:
One hundred patients with CRF who received therapy at the First Affiliated Hospital of Jinzhou Medical University between December 2022 and February 2025 were included. The Depression, Anxiety, and Stress Scale (DASS-21), Satisfaction with Life Scale (SWLS), and Temporal Experience of Pleasure Scale (TEPS) were used to evaluate negative emotions, life satisfaction, and pleasure level, respectively. Pearson's correlation coefficient analyzed the correlation between life satisfaction, pleasure level, and negative emotions. Linear regression analysis identified the factors affecting negative emotions.
Results:
The average DASS-21 score among patients with CRF was 51.90 ± 2.30, with subscale scores of 17.90 ± 1.50 for depression, 18.53 ± 1.18 for anxiety, and 15.47 ± 2.36 for stress, all significantly higher than the domestic norm (P < 0.05). The average SWLS score was 22.17 ± 4.90. Correlation analysis revealed a negative correlation between the SWLS and total DASS-21 scores (P < 0.05), but not with the individual depression, anxiety, or stress dimensions. The average TEPS score was 67.80 ± 8.34. TEPS scores were negatively correlated with the DASS-21 score and the stress dimension (P < 0.05), but not with depression or anxiety. Linear regression analysis showed that TEPS scores significantly influenced DASS-21 scores (P < 0.05).
Conclusion:
Patients with CRF experience high levels of negative emotions, which are negatively correlated with life satisfaction and pleasure. Furthermore, pleasure level had an impact on negative emotions.
Related Concept Videos
Role of Emotions in Social Life
Renal Failure: Dose Adjustments
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Correlations
Correlation and Causation
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
Half-life of a Reaction
Characteristics of Life

