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Updated: Jan 30, 2026

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
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Tenecteplase in large-vessel occlusion with or without thrombectomy: a meta-analysis

Ahmed Alkhiri1, Aser F Alamri1, Fahad Alturki1

  • 1Neuroscience Center of Excellence, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Frontiers in Neurology
|January 29, 2026
PubMed
Summary

Tenecteplase improves outcomes for large-vessel occlusion stroke patients, especially when given before endovascular thrombectomy (EVT) within 4.5 hours. Extended window use with neuroimaging is beneficial for selected patients without EVT access.

Keywords:
bridginglarge-vessel occlusionstroketenecteplasethrombectomy

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