Related Experiment Video
Updated: Jan 30, 2026
Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
Published on: March 24, 2023
Innovative digital approaches to characterize core factors of patients with late-stage knee osteoarthritis: a
Marco Alessandro Minetto1, Elisabetta Quilico1, Federica Massazza2,3
1Division of Physical Medicine and Rehabilitation, Department of Surgical Sciences, University of Turin, Torino, Italy.
Background:
This study aimed to investigate in knee osteoarthritis patients the feasibility of a digital anthropometric approach for body size and composition assessment in combination with assessments of physical and pain characteristics.
Methods:
A convenience sample of 56 patients (34 females) was recruited. Clinical and radiographic evaluation, digital pain drawing and anthropometric assessments, and physical performance tests were performed.
Results:
Pain had an anterior distribution in all patients and several patients showed also a posterior and bilateral distribution. Median values of body fat percentage, fat mass index, and appendicular lean mass index were 28.3%, 7.8 kg/m2, and 8.4 kg/m2 in 19 males and 40.0%, 12.5 kg/m2, 6.8 kg/m2 in 28 females. Most of the patients had fat mass index higher than the cut-points for excess fat, while 2 male patients and none of the female patients had appendicular lean mass index lower than the cut-point for low mass. A relevant impairment of physical performance was observed in all patients.
Conclusion:
Innovative digital tools can be used to quantify the changes in body size and composition and the pain location and extension in patients with late-stage knee osteoarthritis.
Related Concept Videos
01:50Cross-Sectional Research
01:24Finding Volume Using Cross-Sectional Area
01:26Profile Leveling and Cross Sections
01:16Spinal Cord: Cross-sectional Anatomy
Gray Matter and its Components
Central to the gray matter is...
01:29Factors Affecting Protein-Drug Binding: Patient-Related Factors
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
02:10The Nucleosome Core Particle
The paradox
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...