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Low-Grade Appendiceal Mucinous Neoplasm: A Case Highlighting Diagnostic and Management Considerations
Ali Hamdan1, Jana Khalil1, Razan Abou Zeid1
1Department of Internal Medicine, University of Balamand, Beirut, Lebanon, balamand.edu.lb.
Case Reports in Medicine
|January 29, 2026
Summary
Appendiceal mucoceles (AMs), rare mucin accumulations, can be challenging to diagnose. This case highlights the importance of imaging and endoscopy for diagnosing low-grade appendiceal mucinous neoplasms (LAMNs) and preventing complications.
Area of Science:
- Gastroenterology
- Pathology
- Surgical Oncology
Background:
- Appendiceal mucoceles (AMs) are uncommon cystic dilations of the appendix.
- They can result from non-neoplastic or neoplastic conditions, such as low-grade appendiceal mucinous neoplasms (LAMNs).
- Diagnosis is often delayed due to nonspecific symptoms and incidental findings.
Purpose of the Study:
- To report a case of appendiceal mucocele secondary to LAMN in a young adult.
- To emphasize the diagnostic challenges and the utility of combined imaging and endoscopic modalities.
- To highlight the importance of timely surgical intervention.
Main Methods:
- Case report of a 29-year-old female with constipation and abdominal pain.
- Diagnostic workup included abdominal CT and colonoscopy.
- Treatment involved laparoscopic appendectomy with subsequent histopathological confirmation.
Main Results:
- CT revealed a cystic appendiceal structure; colonoscopy showed a mucocele.
- Histopathology confirmed LAMN.
- The patient recovered well post-surgery without complications.
Conclusions:
- Appendiceal mucoceles, especially LAMNs, require a high index of suspicion for accurate diagnosis.
- Multimodal diagnostic approaches (imaging and endoscopy) are crucial.
- Prompt surgical management is essential to prevent rupture and pseudomyxoma peritonei.
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