Noncutaneous Visceral Kaposi Sarcoma of the Stomach and Liver: A Case Report

Kaposi sarcoma (KS) is an angioproliferative neoplasm caused by human herpes virus-8, most commonly affecting immunocompromised individuals, particularly those with HIV/AIDS. While KS typically presents with violaceous cutaneous lesions, visceral involvement, especially in the gastrointestinal and hepatic systems, is rare and often asymptomatic.

We describe an uncommon presentation of AIDS-related KS involving the liver, stomach, and lungs in a 25-year-old male with poorly controlled HIV. Despite the absence of cutaneous manifestations, KS was diagnosed with a high index of suspicion, and appropriate treatment was initiated with antiretroviral therapy along with plans to initiate chemotherapy in the outpatient setting.

This case highlights the importance of considering visceral KS in HIV/AIDS patients even in the absence of skin lesions, as early diagnosis and intervention can improve patient outcomes.