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Yeast-Based Biotechnology for Civilian Security.

Justyna Ruchała1, Roksolana Vasylyshyn1,2, Maciej Wnuk1

  • 1Faculty of Biotechnology, Medical College, University of Rzeszów, Rzeszów, Poland.

Environmental Microbiology Reports
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Yeast biotechnology offers innovative solutions for biosecurity and environmental protection. These microorganisms can detect, neutralize, and prevent biological and chemical threats, enhancing preparedness.

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Area of Science:

  • Microbiology
  • Biotechnology
  • Biosecurity

Background:

  • Yeasts possess versatile applications beyond traditional fermentation.
  • Emerging roles in biosecurity and civilian protection are being explored.
  • Both conventional and non-conventional yeast strains show potential.

Purpose of the Study:

  • To explore yeast's contribution to detecting, neutralizing, and preventing biological and chemical threats.
  • To review current and potential applications of yeast in biosecurity.
  • To highlight yeast-based vaccine platforms and biosensor technologies.

Main Methods:

  • Review of recombinant yeast cell applications in biosensors.
  • Analysis of yeast's role in bioremediation and toxin removal.
  • Examination of yeast-based vaccine platforms (RNA and antigen-display).

Main Results:

  • Recombinant yeast cells are effective in biosensors for various pollutants.
  • Yeast shows promise in bioremediation and toxin neutralization.
  • Yeast-based vaccine platforms offer scalable and sustainable solutions.

Conclusions:

  • Yeast biotechnology provides low-cost, scalable solutions for biodefense.
  • Challenges include biosensor stability, regulatory hurdles, and calibration standardization.
  • Yeast is a resilient component for future environmental protection and biodefense strategies.