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Updated: Jan 31, 2026

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Caught in the Fence: Thrombus Trapped Within Patent Foramen Ovale-Hybrid Transcatheter and Surgical Embolectomy
Asim Mohiuddin1, Amr Marawan1, Khaled Atieh2
1Department of Cardiology, Baylor Scott & White the Heart Hospital Plano, Plano, Texas, USA.
Background:
Clot-in-transit (CIT) and pulmonary embolism (PE) can lead to hemodynamic collapse and death. Thrombolysis or thrombectomy is often required and has been shown to decrease mortality.
Case-Summary:
This patient presented with saddle PE with severe respiratory distress and obstructive shock and later found to have a large clot trapped within the patent foramen ovale (PFO). He inadvertently required a transcatheter thrombectomy of a large PE followed by surgical embolectomy of the CIT from the PFO discovered afterward.
Discussion:
There is no consensus for treatment of CIT; however, this case presents an additional unique challenge with CIT trapped within the PFO. Hemodynamic stability attained following thrombectomy of PE likely contributed to a successful surgical outcome for this patient.
Take-Home Message:
CIT trapped within the PFO in combination with large PE and hemodynamic instability can potentially be treated with transcatheter therapy prior to surgical embolectomy to optimize surgical success.
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