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Open Partial Horizontal Laryngectomies: Functional and Oncologic Outcomes.

Laura Rodrigáñez1, Helena Gómez-Camacho1, Alejandro Castro1

  • 1Oto-rhino-laryngology Department, La Paz University Hospital, Madrid, Spain.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|January 29, 2026
PubMed
Summary
This summary is machine-generated.

Open Partial Horizontal Laryngectomy (OPHL) offers comparable oncologic outcomes to total laryngectomy for selected laryngeal cancer patients. This technique also achieves excellent, stable functional results, preserving voice and swallowing functions.

Keywords:
head and neck cancerlaryngeal cancerlaryngeal function preservationopen partial horizontal laryngectomiesorgan‐preservation protocols

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Area of Science:

  • Otolaryngology
  • Surgical Oncology
  • Laryngeal Cancer Research

Background:

  • Open Partial Horizontal Laryngectomy (OPHL) use has declined with advancements in chemoradiation and transoral techniques.
  • Evaluating the oncologic and functional outcomes of OPHL is crucial for its continued role in laryngeal cancer management.

Purpose of the Study:

  • To analyze the oncologic and functional results of Open Partial Horizontal Laryngectomy (OPHL).
  • To assess the long-term efficacy and safety of OPHL in patients with laryngeal squamous cell carcinoma.

Main Methods:

  • Retrospective case series conducted at a university-affiliated tertiary care center.
  • Included patients with laryngeal squamous cell carcinoma who underwent open horizontal supraglottic laryngectomy (OHSL) or supracricoid partial laryngectomy (SCPL) between 2000 and 2020.

Main Results:

  • 112 patients were analyzed, with 30.4% having T3-T4 tumors.
  • High rates of decannulation (93%) and feeding tube discontinuation (95%) were observed.
  • 5-year laryngeal cancer (LC) rates were 90.2% for T1-T2 and 80.9% for T3-T4 tumors; 5-year laryngeal examination for disease-free survival (LEDFS) was 72.1%.

Conclusions:

  • OPHL in selected patients with early and locally-advanced laryngeal tumors yields oncologic results comparable to total laryngectomy.
  • OPHL provides excellent and stable functional outcomes, preserving essential functions post-surgery.