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Published on: May 13, 2022
Innovative Lipid-Based Nanobiotechnology: Diagnostics and Medicine
Sung Eun Seo1, Kyung Ho Kim1, Shubham Singh2
1SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon 16419, Republic of Korea.
This review summarizes advanced lipid-based nanomaterials for medicine and diagnostics. These versatile biomaterials offer targeted drug delivery, cancer therapy, and immune modulation, advancing nanobiotechnology applications.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Drug Delivery
Background:
- Lipid-based nanomaterials are crucial in advanced therapeutics and diagnostics.
- Their properties are dictated by chemical structure, functionality, and synthesis.
- Bioengineered lipid-based nanomaterials are a primary focus in nanobiotechnology.
Purpose of the Study:
- To review the state-of-the-art in integrating lipid-based natural biomaterials.
- To emphasize broad applications, particularly in therapeutics and diagnostics.
- To highlight the utilization of bioengineered lipid-based nanomaterials.
Main Methods:
- Review of current literature on lipid-based nanomaterials.
- Analysis of material properties, fabrication processes, and applications.
- Discussion of surface engineering with functional moieties.
Main Results:
- Lipid-based nanomaterials demonstrate versatility as drug-delivery nanocarriers.
- They are effective for targeting specific cancer cells and for controlled immune therapies.
- Surface engineering enables integration of signaling pathway mediators, nucleic acid drugs, and targeting proteins.
Conclusions:
- Innovative lipid-based nanobiotechnology offers significant potential in medicine and diagnostics.
- The review covers materials, fabrication, and applications of these advanced biomaterials.
- Further research in bioengineered lipid-based nanomaterials will drive therapeutic and diagnostic advancements.
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