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Assessment of Cardiovascular Risk Factors and Selected Echocardiographic Parameters in Male Patients with Psoriasis
Sylwia Adamczyk1, Michał Miszczak2, Aldona Pietrzak3
1Health Clinic of the John Paul II Catholic University of Lublin, Lublin, Poland.
Insights
Psoriasis patients show increased cardiovascular risk, including subclinical cardiac damage. Early screening and preventive strategies are crucial for managing this heightened risk in individuals with psoriasis.
Area of Science:
- Cardiology
- Dermatology
- Public Health
Background:
- Psoriasis is linked to a higher incidence of cardiovascular diseases like myocardial infarction and coronary artery disease.
- This study investigates cardiovascular risk factors and subclinical cardiac damage in male psoriasis patients.
Purpose of the Study:
- To assess cardiovascular risk factors in adult male patients with psoriasis.
- To evaluate left ventricular diastolic function using echocardiography.
- To determine the association between psoriasis and subclinical cardiac damage.
Main Methods:
- An observational study comparing 77 adult male psoriasis patients with a control group.
- Echocardiography was performed to assess left ventricular diastolic function.
- Logistic regression was used to identify independent risk factors for cardiac damage.
Main Results:
- Psoriasis patients exhibited higher BMI, C-reactive protein levels, and hypertension rates.
- Smoking was more prevalent in the psoriasis group.
- Psoriasis patients had increased left atrial volume index and left ventricular mass index, indicating subclinical cardiac damage (OR=2.77, 95% CI: 1.07-7.83).
Conclusions:
- Psoriasis independently increases the risk of subclinical cardiac damage.
- Early cardiovascular disease screening and preventive measures are recommended for psoriasis patients.
- Cardiac damage in psoriasis patients is associated with age, hypertension, and antihypertensive medication use.
Introduction:
Psoriasis is associated with an increased risk of cardiovascular disease, including myocardial infarction and coronary artery disease.
Methods:
This single-center observational study assessed cardiovascular risk factors in 77 adult male patients with psoriasis compared with a control group. All participants underwent echocardiography to evaluate left ventricular diastolic function.
Results:
Patients with psoriasis had a higher body mass index (BMI) (p = 0.062), elevated C-reactive protein levels (p < 0.001), and more frequent hypertension (p = 0.001). Past and current smoking was significantly more common in the psoriasis group (p < 0.05). Echocardiographic parameters were generally higher in psoriasis patients, particularly the left atrial volume index (LAVI) (median 23.72 vs. 19.5 mL/m2; p < 0.01) and left ventricular mass index (LVMI) (median 99.84 vs. 93.70 g/m2; p < 0.05). Subclinical cardiac damage occurred more frequently in psoriasis patients (OR = 3.37, 95% CI: 1.39-9.1), remaining significant after adjustment for hypertension, smoking, and BMI (OR = 2.77, 95% CI: 1.07-7.83). Logistic regression indicated that cardiac damage was associated with age, hypertension, and antihypertensive use. Psoriasis independently increased the risk of subclinical cardiac damage after adjustment for age and hypertension.
Conclusion:
Patients with psoriasis should be screened early for cardiovascular disease and preventive strategies introduced to reduce long-term risk.
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