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Updated: Jan 31, 2026

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications
Published on: April 21, 2016
Preparation and application of the transistor based on D-A isoindigo copolymer/GR blend for the detection of circular
Caiyuan Liao1, Fayu Wang1, Long Fang1
1Hubei Province Key Laboratory of Biotechnology of Chinese Traditional Medicine, College of Health Science and Engineering, Hubei University, Wuhan, 430062, China.
Abstract:
A field-effect transistor based on donor-acceptor (D-A) copolymer/graphene (GR) blends was successfully developed, with systematic optimizations implemented for key parameters including the concentration of polymeric monomers, selection of blending materials, mass ratio of blended components, and post-deposition annealing temperature of the composite films. The D-A copolymer was synthesized by Stille polycondensation with isoindigo as the acceptor (A) unit and thieno [3,2-b] thiophene as the donor (D) unit. The PIID-C10-TT/GR blend with a ratio of 95/5 exhibited the optimal performance in the device, achieving a carrier mobility of 0.123 ± 0.014 cm2/(V·s), a subthreshold swing of 308.00 ± 34.87 mV/dec, and an on/off ratio of 1.27 × 103. The novel Ab/ADP/GR-FET biosensor exhibited excellent sensing performance for the detection of the EpCAM biomarker, with a detection range of 0.05-20 ng/mL, a lower detection limit (LOD) of 24 pg/mL, and high selectivity. Notably, it demonstrated robust detection capability for circulating tumor cells (MCF-7), showing a linear response range from 5 to 50 cells. These studies indicated that the electrochemical field-effect transistor (EFET) based on the PIID-C10-TT/GR blend as a semiconductor material holds significant potential for biosensing applications.
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