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Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY
Published on: June 30, 2016
One-year prospective study of a HEMA-based hydrophobic acrylic trifocal IOL (Clareon PanOptix): visual performance,
Yoshifumi Fujita1, Yuya Nomura1, Toru Sugita2
1Fujita Eye Clinic, Tokushima, Japan.
Abstract:
While Clareon monofocal intraocular lens (IOL) has been reported to be free from surface light scattering and glistenings, it remains unknown whether Clareon PanOptix IOL develops these optical phenomena. This study aimed to evaluate one-year surgical outcomes of this IOL, with a focus on visual function, patient-reported satisfaction, and clarity of IOL optics. A prospective study was conducted in 78 eyes of 39 patients undergoing bilateral implantation of toric or non-toric Clareon PanOptix IOLs. Postoperative examinations were conducted at 1, 6, and 12 months. At 12 months, bilateral uncorrected visual acuity (BUCVA) and bilateral distance-corrected visual acuity (BDCVA) were better than 20/20 at 40 cm, 60 cm, and 5 m. No cases of surface light scattering or glistenings were observed. Spectacle independence was achieved in 84.2% of patients. While patient satisfaction with vision in daily life and daytime driving was high, approximately half of the patients reported some difficulty with night driving. The Clareon PanOptix provided satisfactory surgical outcomes, with no formation of surface light scattering or glistenings during the one-year follow-up period.
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