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Tailored vertebral artery mobilisation in complex craniovertebral junction surgery
Ved Prakash Maurya1, Ashutosh Kumar1, Anantha Chaitanya J1
1Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, 226014, India.
Insights
Tailored vertebral artery mobilization (VAM) offers a safe surgical approach for complex craniovertebral junction anomalies involving aberrant vertebral arteries. This technique improves patient outcomes by decompressing neurovascular structures and stabilizing the C1-C2 joint.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Vascular Surgery
Background:
- Complex craniovertebral junction (CVJ) anomalies present diverse challenges, including atlantoaxial dislocation and aberrant vertebral artery (VA) courses.
- Accessing the C1-C2 joint for surgical management is often complicated by the anomalous anatomy of the VA, posing risks to neurovascular structures.
Purpose of the Study:
- To describe surgical nuances and share experience with tailored vertebral artery mobilization (VAM) for managing complex CVJ anomalies.
- To evaluate the efficacy and safety of VAM in providing a surgical corridor for C1-C2 joint access without increasing neurovascular injury risk.
Main Methods:
- Retrospective observational study of 32 patients with CVJ anomalies operated between January 2018 and December 2024.
- Collected clinical, radiological, and operative data; compared outcomes of patients with anomalous VA course (study group) versus normal VA course (control group).
- Assessed clinicoradiological improvement at three-month follow-up using Nurick's grading scale.
Main Results:
- A total of 32 patients were analyzed, with a median pre-operative Nurick's grade of 4.
- Eighteen patients underwent unilateral VAM, and fourteen underwent bilateral VAM.
- Statistically significant improvement in median post-operative Nurick's grade to 3 (P=0.002) at three months, with a mean follow-up of 28.5 months and no procedure-related mortality.
Conclusions:
- Tailored VAM is an effective surgical strategy for complex CVJ pathologies with anomalous VA.
- This technique establishes a safe surgical corridor for C1-C2 joint access, minimizing risks to neurovascular structures.
- VAM contributes to improved stability and patient recovery in CVJ anomaly management.
Abstract:
The surgical management of complex craniovertebral junction (CVJ) anomaly requires decompression of the neurovascular structures. Besides the atlantoaxial dislocation, the spectrum of anomalies noticed at CVJ is myriad. This includes an occipitalised C1 arch, hypoplasia of the C2 pedicle, basilar invagination, a high-riding vertebral artery (VA), a lower origin of the posterior inferior cerebellar artery (PICA), and unilateral or bilateral VA hypoplasia. The aberrant course of the VA has been the most challenging entity to access the C1-C2 joint. The atlantoaxial joint remodelling and reorientation play a vital role in achieving stability in this region. Here, we aim to describe the surgical nuances and share our experience with tailored VA mobilisation for the efficient management of CVJ anomalies. All cases of CVJ anomaly operated between January 2018 and December 2024 were included in this retrospective observational study. The clinical, radiological and operative details were collected from the neurosurgery record-keeping system. The surgical nuances and follow-up recovery of patients with VA anomaly (study group) were compared with those of patients having a normal course of VA (control group). Postoperative clinicoradiological improvement was evaluated at three-month follow-up visits. A total of 32 patients were analysed with a mean age of 47.21 ± 16.20 years. The median pre-operative Nurick's grade amongst the study population was 4 (IQR: 3,4 and Range: 3-5). Eighteen patients (18/32, 56.3%) underwent unilateral VA mobilisation (VAM), whereas fourteen patients (14/32, 43.7%) underwent bilateral VAM. After surgery, at the three-month follow-up visit, the median post-operative Nurick's grade was 3 (IQR: 2,3 and Range: 2-5), which was statistically significant (P = 0.002). The mean follow-up duration was 28.5 months (range: 6-85 ± 13.6 months) without any procedure-related mortality. Tailored VAM is an excellent surgical strategy for the management of complex CVJ pathology with an anomalous VA course. It provides a safe surgical corridor to access the C1-C2 joint without increasing the risk of injury to neurovascular structures.
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