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Related Experiment Video

Updated: Jan 31, 2026

Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.
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Genetic dynamics drive maize growth and breeding.

Chengxiu Wu1,2, Zedong Geng1,2, Weikun Li1,2

  • 1National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, 430070, China.

Genome Biology
|January 30, 2026
PubMed
Summary

This study reveals the genetic basis of maize growth dynamics using high-throughput phenotyping and genome-wide association studies. Key genes influencing plant architecture and development were identified, aiding predictive breeding strategies.

Keywords:
Breeding designGrowth dynamicsImage-based traitsMaizeTemporal genetic regulationTrajectory modeling

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Area of Science:

  • Plant genetics
  • Developmental biology
  • Quantitative genetics

Background:

  • Phenotypic diversity in plants is driven by development and genomic variation.
  • The genetic underpinnings of maize growth dynamics are not well understood.

Purpose of the Study:

  • To investigate the genetic architecture of maize growth dynamics.
  • To identify quantitative trait loci (QTLs) and genes controlling growth variation across developmental stages.
  • To explore the role of temporal genetic regulation in shaping plant architecture.

Main Methods:

  • Analysis of 679 maize inbred lines with ~2.8 million SNPs.
  • High-throughput phenotyping capturing over 1 million RGB images across 18 growth stages.
  • Genome-wide association studies (GWAS) to identify QTLs for 67 image-based traits (i-traits).

Main Results:

  • Identified 857 QTLs for growth variation, with most being period-specific dynamic QTLs.
  • Discovered cryptic pleiotropic QTLs suggesting developmental genetic relocations.
  • Characterized novel gene functions (e.g., BRD1, ZmGalOx1) impacting plant architecture.
  • Enhanced heritability estimates for mature traits by an average of 6.2%.

Conclusions:

  • Elucidated the spatial-temporal genetic architecture of maize growth dynamics.
  • Provided novel insights into developmental rewiring of epistatic networks.
  • Supported ontogeny-driven predictive breeding strategies for maize improvement.