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Updated: Jan 31, 2026

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Assessment and Characterization of Hyaloid Vessels in Mice
Published on: May 15, 2019
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Malignant glaucoma with variable outcomes after irido-zonulo-hyaloid-vitrectomy-bilateral involvement: a case report
Na Li1,2, Yalong Dang3,4, Fang Lei2
1Department of Ophthalmology, Sanmenxia Eye Hospital/Sanmenxia Central Hospital Affiliated to Henan University of Science and Technology, Sanmenxia, China.
Journal of Medical Case Reports
|January 30, 2026
Summary
Early surgical intervention, like irido-zonulo-hyaloid-vitrectomy, is crucial for managing malignant glaucoma. Prompt treatment prevents vision loss and complications such as macular edema, ensuring better outcomes.
Area of Science:
- Ophthalmology
- Surgical Complications
Background:
- Malignant glaucoma is a rare but severe complication post intraocular surgery (2-4% incidence).
- It stems from aqueous humor flow obstruction, causing increased posterior pressure and potential vision loss.
- Early intervention and anti-inflammatory strategies are key for managing this condition.
Purpose of the Study:
- To highlight the significance of timely surgical intervention in malignant glaucoma.
- To compare outcomes of delayed versus early surgical management in a bilateral case.
Main Methods:
- A case study of a 56-year-old woman with bilateral malignant glaucoma.
- Treatment comparison: delayed medication and laser followed by vitrectomy in the right eye versus early cataract extraction and vitrectomy in the left eye.
Main Results:
- Delayed treatment in the right eye led to limited success and subsequent macular cystoid edema.
- Early intervention in the left eye resulted in optimal intraocular pressure control and preserved vision without complications.
Conclusions:
- Early irido-zonulo-hyaloid-vitrectomy is vital for effective malignant glaucoma management.
- Prompt surgical intervention prevents complications like macular edema and improves visual prognosis.
- Tailored anti-inflammatory management further enhances outcomes in bilateral malignant glaucoma.
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