Developing Patient-Centered Clinical Trials: Implications for Incorporating Patient Perspectives

Area of Science:

• Surgical research
• Patient-centered care
• Qualitative research methodology

Background:

• Clinical trials are essential for advancing surgical research.
• Ensuring surgical research aligns with patient priorities is critical for relevance and efficacy.
• Groin hernias represent a common surgical condition where patient perspectives can inform research direction.

Purpose of the Study:

• To explore female patients' perspectives on research priorities for groin hernias.
• To understand patient preferences regarding clinical trial participation.
• To identify key outcomes important to patients undergoing evaluation for groin hernias.

Main Methods:

• An exploratory qualitative study design was employed.
• Semi-structured interviews were conducted with 34 female patients.
• Grounded theory principles guided data analysis to identify emergent themes.

Main Results:

• Patients expressed significant interest in nonoperative management options.
• A strong willingness to participate in clinical trials was reported.
• Key outcomes of importance included pain management, recovery speed, and overall quality of life.

Conclusions:

• Patient-centered approaches are vital for designing relevant surgical trials.
• Incorporating patient priorities, such as nonoperative options and quality of life, enhances trial design.
• Future surgical research, particularly for groin hernias, should actively involve patient perspectives to ensure alignment with patient needs.