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Updated: Jan 31, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Prevalence of Right-to-Left Shunting on Echocardiography in Patients with Cancer and Stroke
Sanaz G Biglou1,2, Ronda Lun3,4, Tim Ramsay2,5
1Faculty of Medicine, University of Ottawahttps://ror.org/03c4mmv16, Ottawa, ON, Canada.
Abstract:
The presence of right-to-left shunt has been proposed as a prominent mechanism of paradoxical embolism in patients with active cancer. We conducted a retrospective observational study including patients presenting to the Ottawa Hospital between January 2020 and December 2022 with ischemic stroke with and without active cancer. Among 491 patients (36.9% female, median age 53), 43 (8.8%) had active cancer, with 12 (27.9%, 95% CI 15-44) having a shunt. Of 448 patients without cancer, 133 (29.7%, 95% CI 25-34) had a shunt. Overall, our finding does not support the hypothesis that cancer-associated stroke is related to right-to-left shunting.
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