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Case Report: Pathological confirmation and aggressive postoperative recurrence of WHO grade III rhabdoid meningioma
Rui Xu1,2, Wei Wang1, Zhen Wang1
1Department of Neurosurgery, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Abstract:
Rhabdoid meningioma (RM), a rare WHO grade III meningioma subtype, features high invasiveness, poor prognosis, and no effective therapies, often being misdiagnosed with other intracranial tumors clinically, such as brain metastases and WHO grade II meningiomas. We report a 39-year-old female admitted for 6-month headaches. Brain magnetic resonance imaging showed a well-circumscribed, heterogeneously enhancing tumor with severe peritumoral edema in the right temporal lobe, initially suspected to be a WHO grade II meningioma; RM was confirmed postoperatively. The tumor recurred 1 month after the first surgery, and the patient died of intracranial hypertension 1 month after the reoperation. This case highlights the need for immediate adjuvant chemoradiotherapy postoperatively.
Insights
Rhabdoid meningioma (RM), a rare aggressive brain tumor, is often misdiagnosed. This case underscores the critical need for prompt adjuvant chemoradiotherapy following surgery for RM.
Area of Science:
- Neuro-oncology
- Pathology
Background:
- Rhabdoid meningioma (RM) is a rare, aggressive WHO grade III meningioma subtype.
- It presents with high invasiveness, poor prognosis, and limited therapeutic options.
- Clinical misdiagnosis is common, often confused with brain metastases or WHO grade II meningiomas.
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