Related Experiment Video
Updated: Jan 31, 2026

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI
Published on: November 27, 2019
Neurosynth Compose: A web-based platform for flexible and reproducible neuroimaging meta-analysis
James D Kent1, Nicholas Lee1, Angela R Laird2
1Department of Psychology, University of Texas at Austin, Austin, TX, United States.
Neurosynth Compose offers a streamlined platform for creating reproducible neuroimaging meta-analyses. This tool enhances data synthesis by integrating automated collection with expert curation, fostering a collaborative knowledge base for functional neuroimaging research.
Area of Science:
- Neuroscience
- Cognitive Science
- Data Science
Background:
- The exponential growth in functional neuroimaging studies complicates synthesizing research findings.
- Existing automated platforms have limitations in addressing complex research questions.
- Manual meta-analyses are time-consuming, lack reproducibility, and risk data loss.
Purpose of the Study:
- Introduce Neurosynth Compose, a web-based platform to simplify the creation of transparent and reproducible neuroimaging meta-analyses.
- Address the limitations of current meta-analysis methods in functional neuroimaging.
Main Methods:
- User-friendly interface for study curation and annotation following PRISMA guidelines.
- Integration with NeuroStore database (30,000+ studies) for pre-extracted activation coordinates.
- Utilizes Neuroimaging Meta-Analysis Data Standard (NiMADS) and NiMARE Python library for analysis.
- Supports local or cloud execution with portable bundles.
Main Results:
- Streamlines the creation of high-quality neuroimaging meta-analyses.
- Facilitates interactive review and rapid sharing of results.
- Encourages a crowdsourced knowledge base through shared annotations and meta-analyses.
- Enables the development of continuously updated 'living' meta-analyses.
Conclusions:
- Neurosynth Compose enhances the efficiency, transparency, and reproducibility of neuroimaging meta-analyses.
- The platform fosters collaboration and the creation of a dynamic, evolving knowledge base in the field.
- Facilitates the synthesis of functional neuroimaging data for advancing research.
Related Concept Videos
Directing Effect of Substituents: meta-Directing Groups
meta-Directing Deactivators: –NO2, –CN, –CHO, –⁠CO2R, –COR, –CO2H
¹H NMR of Conformationally Flexible Molecules: Temporal Resolution
Classification of Titrimetric Analysis Based on Reaction Types
Titrations between an acid and a base lead to neutralization reactions that form...
¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR
Qualitative Analysis
For instance, group IV...

