Safety and Efficacy of Microvascular Decompression for Trigeminal Neuralgia in the Octogenarian Population: Insights

Mohammadmahdi Sabahi1, Brandon Kaye2, Neel Balusa2

  • 1Department of Neurological Surgery, Pauline Braathen Neurological Center, Cleveland Clinic Florida, Weston , Florida , USA.

Neurosurgery
|January 30, 2026
PubMed
Abstract

Insights

Microvascular decompression (MVD) offers effective trigeminal neuralgia (TN) pain relief for octogenarians, comparable to younger patients. Age is not a barrier; comprehensive health assessment is key for MVD suitability in elderly TN patients.

Area of Science:

  • Neurosurgery
  • Geriatric Medicine
  • Pain Management

Background:

  • Microvascular decompression (MVD) is the leading long-term treatment for trigeminal neuralgia (TN).
  • Elderly patients often face a dilemma between MVD risks and less durable ablative procedures.
  • This study compares MVD safety and efficacy in octogenarians versus younger patients.

Purpose of the Study:

  • To evaluate the safety and efficacy of MVD in octogenarian patients (≥80 years) with TN.
  • To compare outcomes between octogenarian and non-octogenarian TN patients undergoing MVD.
  • To determine if age alone should influence MVD treatment decisions for TN.

Main Methods:

  • A matched cohort analysis of 152 patients (33 octogenarians, 119 non-octogenarians) after propensity score matching.
  • Exclusion of patients with prior MVD procedures.
  • Comparison of preoperative characteristics, postoperative complications, and pain scores.

Main Results:

  • Octogenarians had lower BMI and higher rates of preoperative arrhythmias.
  • New or worsened arrhythmias were more common in octogenarians post-MVD (6.1% vs 0%).
  • No significant differences in length of stay, readmission, reoperation, or other complications; similar pain relief and BNI scores were observed in both groups.

Conclusions:

  • Octogenarians achieve comparable pain relief and postoperative outcomes with MVD for TN as younger patients.
  • Arrhythmia is a notable postoperative complication in octogenarians, but overall outcomes remain similar.
  • MVD is a viable treatment option for elderly TN patients, emphasizing individualized health assessments over age alone.

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