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Updated: Jan 31, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Guideline commentary on the ESC/EACTS 2024 guidelines for atrial fibrillation: a focus on managing AF in the older
Riyaz A Kaba1,2,3,4, Chakravarthi Rajkumar5,6, Francesco Mattace-Raso7
1Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's, University of London, St George's Hospital Medical School, London, England, UK.
Insights
New European Society of Cardiology guidelines offer updated atrial fibrillation (AF) management strategies, particularly for older adults. These recommendations address stroke risk, anticoagulation, and interventions like AF ablation, considering the complexities of aging patients.
Area of Science:
- Cardiology
- Geriatrics
- Clinical Guidelines
Background:
- Atrial fibrillation (AF) increases risks of stroke, heart failure, and mortality.
- AF management in older adults is complicated by comorbidities, frailty, and polypharmacy.
- European Society of Cardiology (ESC) guidelines were recently updated.
Purpose of the Study:
- To discuss key changes in the 2024 ESC guidelines for AF management.
- To analyze the implications of these guidelines for older patients.
- To provide perspectives on future research and guideline development for the aging population.
Main Methods:
- Guideline commentary and analysis.
- Review of updated ESC/EACTS recommendations for AF.
- Focus on implications for geriatric populations.
Main Results:
- Updated recommendations impact AF management approach, stroke/bleeding risk assessment, and anticoagulation.
- Changes in evidence levels for interventions like left atrial appendage closure and AF ablation.
- Specific considerations for older adults with AF are highlighted.
Conclusions:
- The 2024 ESC guidelines necessitate a review of AF management in older adults.
- Future trials and guidelines should better address the heterogeneity of the aging population.
- Optimizing AF care requires tailored approaches for elderly patients.
Abstract:
Atrial fibrillation (AF) is associated with increased risks of stroke, heart failure and mortality. Rate and rhythm control are used to manage symptoms and improve quality of life, and restoration of normal sinus rhythm is also important for many, but not all, patients. AF is more prevalent in older adults, for whom AF management can be compounded by comorbidities and ongoing conditions, frailty, cognitive issues and polypharmacy. The European Society of Cardiology (ESC) in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS) recently updated recommendations for AF management, which may have implications for older adults in terms of overarching AF management approach, stroke and bleeding risk assessments and anticoagulation considerations. In addition, guideline recommendations and associated levels of evidence have changed for some interventions, such as left atrial appendage closure and AF ablation. In this guideline commentary, key aspects, changes and recommendations in the 2024 ESC guidelines are discussed in the context of older patients, as well as perspectives on specifically addressing the diverse ageing population in future clinical trials and practice guidelines.
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