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Updated: Feb 1, 2026
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Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain
Published on: July 18, 2016
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Staying Active: Promoting Activity Engagement for Poststroke Pain Management With Insights From Ecological Momentary
Ariz Keshwani1, Riddhi D Patel1, Sahil Doshi1
1Northwestern University Feinberg School of Medicine, Chicago, IL.
Archives of Physical Medicine and Rehabilitation
|January 30, 2026
Summary
Activity engagement impacts post-stroke pain. Social interaction may reduce current pain, while physical activity and daily living activities may decrease future pain.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Pain Management
Background:
- Post-stroke pain is a common and debilitating condition affecting recovery.
- Understanding factors influencing pain is crucial for effective management strategies.
Purpose of the Study:
- To investigate the relationship between daily activity engagement and current/future pain in individuals following a stroke.
- To explore how different types of activities and social interactions affect pain levels.
Main Methods:
- A prospective observational study involving 202 individuals with mild-to-moderate stroke.
- Utilized smartphone-based ecological momentary assessment (EMA) for real-time monitoring of pain and activity engagement over two weeks.
- Employed multilevel models to analyze concurrent and time-lagged associations between pain and activity.
Main Results:
- Concurrent associations: Physical activities, time with care providers, and hospitalizations/clinic visits linked to increased pain. Social interactions (coworkers, friends, spouse) linked to decreased pain.
- Time-lagged associations: Physical activities and activities of daily living (ADL) associated with reduced subsequent pain. Time with care providers and hospital stays associated with increased subsequent pain.
Conclusions:
- Ecological momentary assessment (EMA) offers valuable real-time insights into post-stroke pain and activity dynamics.
- Promoting social interaction may alleviate current pain.
- Encouraging physical activity and participation in activities of daily living (ADL) shows potential for reducing future pain.
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