Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bones of the Lower Limb: Tibia and Fibula01:10

Bones of the Lower Limb: Tibia and Fibula

9.3K
The tibia is the main weight-bearing bone of the lower leg. It is larger than the fibula with which it is paired. The tibia is also the second longest bone in the body and is located right below the skin. The proximal end of the tibia forms the medial and the lateral condyle, which articulates with the condyles of the femur to form the knee joint. Between the articulating surfaces is the irregular elevated area known as the intercondylar eminence that serves as the inferior attachment point for...
9.3K
Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

10.8K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
10.8K
Outcomes of Glycolysis01:13

Outcomes of Glycolysis

107.2K
Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
107.2K
Long-term Depression01:05

Long-term Depression

33.3K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.3K
Long-term Depression01:03

Long-term Depression

3.4K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.4K
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

3.9K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
3.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intra-Articular Influence of PETS Technique Treating Limb Length Discrepancy for Both Femur and Tibia: Comment on Study By Lee et al.

Journal of pediatric orthopedics·2026
Same author

Management of spastic diplegic cerebral palsy using ayurveda.

Bioinformation·2026
Same author

Is guided growth a viable treatment option for angular deformity correction in distal renal tubular acidosis patients?

Journal of clinical orthopaedics and trauma·2025
Same author

Factors Affecting Lateral Overgrowth in Operatively Treated Lateral Condyle Fractures in Children: Comment on Study By Bloodworth et al.

Journal of pediatric orthopedics·2025
Same author

Modified Stoppa Approach Alone or in Combination with a Lateral Window for Acetabular Fractures Involving Both Columns.

Hip & pelvis·2025
Same author

Plain radiographs predict retained foreign bodies in forgotten rubber band syndrome - A case report and literature review.

Journal of clinical orthopaedics and trauma·2025

Related Experiment Video

Updated: Feb 1, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction
05:34

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

Published on: July 18, 2025

536

Paley Va Tibia hemimelia: challenges and mid-term outcomes.

Ayesha Mohapatra1, Prateek Behera2

  • 1Othopedics, AIIMS Bhopal, Bhopal, Madhya Pradesh, India ayeshamohapatraortho@gmail.com.

BMJ Case Reports
|January 30, 2026
PubMed
Summary
This summary is machine-generated.

This study presents a limb reconstruction for a child with congenital tibia absence, avoiding amputation. Staged surgeries achieved a stable, plantigrade foot and mobile knee, demonstrating reconstruction viability for non-amputation cases.

Keywords:
Congenital disordersOrthopaedics

More Related Videos

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
07:59

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration

Published on: April 4, 2022

1.8K
Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis
02:08

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis

Published on: July 5, 2024

1.5K

Related Experiment Videos

Last Updated: Feb 1, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction
05:34

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

Published on: July 18, 2025

536
Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
07:59

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration

Published on: April 4, 2022

1.8K
Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis
02:08

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis

Published on: July 5, 2024

1.5K

Area of Science:

  • Orthopedic Surgery
  • Pediatric Limb Reconstruction
  • Congenital Limb Deficiencies

Background:

  • Congenital absence of the tibia presents significant challenges in pediatric limb reconstruction.
  • Cultural factors, such as parental non-acceptance of amputation, necessitate alternative treatment strategies.
  • Paley Va (Jones Ia) axial longitudinal intercalary deficiency requires complex, staged surgical interventions.

Purpose of the Study:

  • To describe a staged surgical reconstruction for an infant with congenital tibia absence and associated foot and knee deformities.
  • To evaluate the short-term outcomes of limb reconstruction in a case where amputation was culturally unacceptable.
  • To present an alternative to amputation for severe limb deficiencies.

Main Methods:

  • Initial surgery involved soft tissue release, fibular shortening, and talus-fibula fusion.
  • Subsequent surgery included Weber patelloplasty with distal patellar rotation and fusion to the proximal fibula.
  • Management of complications such as femoral osteomyelitis, skin necrosis, and non-union was performed.

Main Results:

  • The child achieved a stable, plantigrade foot and a mobile knee with active movements after three years.
  • The patient was able to walk with the aid of a knee-foot-ankle orthosis.
  • Complications were managed appropriately, and the reconstructed limb, while not normal, provided functional improvement.

Conclusions:

  • Limb reconstruction can be a viable option for children with congenital tibia absence when parents decline amputation.
  • Staged surgical procedures, despite their prolonged duration and potential complications, can yield positive functional outcomes.
  • This approach offers a limb-sparing alternative for severe pediatric limb deficiencies, prioritizing function and patient mobility.