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Updated: Feb 2, 2026

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
Published on: September 2, 2025
Approaches to needle navigation in interstitial brachytherapy using infrared tracking and radiography
Veronika Kreß1,2, Ricarda Merten1,2, Christoph Bert1,2
1Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
This study introduces two novel needle navigation methods using infrared tracking and X-ray imaging to reduce radiation exposure and procedure time in gynecologic brachytherapy. These techniques accurately guide needle placement, improving brachytherapy workflows.
Area of Science:
- Medical Physics
- Radiotherapy
- Surgical Navigation
Background:
- Intraoperative cone-beam computed tomography (CBCT) aids gynecologic brachytherapy applicator positioning but increases radiation exposure and procedure time due to repeated imaging.
- Accurate 3D applicator positioning is crucial for effective brachytherapy treatment delivery.
Purpose of the Study:
- To develop and evaluate methods for intraoperative needle path navigation and correction, reducing the need for multiple CBCT scans.
- To enable accurate, real-time needle guidance by combining infrared tracking with planar X-ray imaging.
Main Methods:
- Real-time tracking of a brachytherapy needle using an infrared-reflective tool.
- 3D needle tip localization via backprojection from two planar X-ray images, reconstructing the needle path with splines.
- A secondary method utilizing one planar X-ray image and prior CBCT bending information for needle prediction.
Main Results:
- The two-X-ray-image method achieved needle path reconstruction with <1 mm deviation from CBCT reference scans.
- The single-scan approach with prior bending data showed promising results with <1.3 mm tip deviation.
- Both methods were validated against CBCT ground-truth in preclinical studies.
Conclusions:
- The developed needle navigation methods are feasible for preclinical applications.
- These techniques show potential to enhance and expedite clinical brachytherapy implantation workflows.
- Improved needle guidance can lead to more efficient and safer radiotherapy procedures.
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