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Four New Triterpenoids From Rubus pirifolius Smith
Xiao-Yan Ning1,2, Mei-Fang Huang1,2, Wen-Jiao Chen1,2
1Guangxi University of Chinese Medicine, Nanning, P. R. China.
Abstract:
Four new triterpenoids, pirifoliusic acids B-E, together with seven known compounds (5-11), have been isolated from Rubus pirifolius Smith. All these structures were determined by spectroscopic techniques. All the isolated triterpenoids were assessed for cytotoxicity against HL-60 (leukemia), A549 (lung), SMMC-7721 (liver), MDA-MB-231 (breast), and SW480 (colon) cancer cell lines. Among them, compounds 10 and 11 exhibited significant cytotoxicities against these five cancer cell lines.

