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Updated: Feb 2, 2026

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse
Published on: March 2, 2018
Metachronous development of bilateral external auditory canal cancer
Hiroaki Masuda1, Kazushi Fujiyama2, Sanami Azuma2
1Department of Otolaryngology and Head and Neck Surgery, NTT Medical Center Tokyo, Tokyo, Japan; Department of Otolaryngology and Head and Neck Surgery, Faculty of Medicine, the University of Tokyo, Tokyo, Japan.
Abstract:
Cancer originating from the external auditory canal (EAC) is rare, which precludes a clear understanding of the disease and its management approaches. We present an extremely rare case of bilateral auditory canal carcinoma that occurred heterochronously. Bilateral treatments resulted in good disease control and EAC structure preservation, which could accommodate various hearing aid options after cancer treatment. While disease control is the most crucial aspect to be considered when choosing a treatment of EAC cancer, one should also consider potential hearing ability in patients post-surgery, particularly in those with bilateral lesions, as it greatly influences the quality of life.
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