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Updated: Feb 2, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Endovascular Repair for Type B Aortic Dissection Accompanied by Retrograde Intramural Haematoma
Xiaolang Jiang1,2, Lingwei Zou1,2, Hao Liu1,2
1Department of Vascular Surgery, Institute of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Thoracic endovascular aortic repair (TEVAR) is effective for type B aortic dissection (TBAD) with retrograde intramural hematoma (RTIMH) extending to zone 0. However, patients with RTIMH involving the proximal ascending aorta require closer follow-up due to higher reintervention rates.
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Interventional Cardiology
Background:
- Type B aortic dissection (TBAD) with retrograde intramural hematoma (RTIMH) presents complex management challenges.
- RTIMH extending to the proximal aorta (zone 0-2) may influence treatment outcomes.
- Thoracic endovascular aortic repair (TEVAR) is an evolving treatment for complex aortic pathologies.
Purpose of the Study:
- To evaluate the outcomes of TEVAR in patients with TBAD and RTIMH involving zone 0-2.
- To compare outcomes between patients with RTIMH involving zone 0 versus those with RTIMH confined to zones 1 and 2.
- To identify factors associated with adverse aortic events (AAEs) after TEVAR.
Main Methods:
- Retrospective multicenter study of 155 patients undergoing TEVAR for TBAD with RTIMH.
- Patients were stratified into two groups: RTIMH involving zone 0-2 (group 1) and RTIMH in zones 1-2 only (group 2).
- Primary endpoint was any AAE, including dissection progression, aorta-related mortality, reintervention, and complications.
Main Results:
- No significant difference in overall AAEs between groups (9.0% total).
- Group 1 patients were younger and had more primary entry tears at the inner aortic arch curvature.
- Freedom from reintervention was significantly lower in group 1 (79.1%) compared to group 2 (93.3%).
Conclusions:
- TEVAR is a viable treatment for selected TBAD patients with RTIMH extending to zone 0.
- Higher reintervention rates in patients with RTIMH propagation into the proximal ascending aorta necessitate vigilant monitoring.
- Close follow-up is crucial for patients with RTIMH involving zone 0 after TEVAR.
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