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Updated: Feb 3, 2026

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
Published on: June 18, 2020
Letter to Editor: Correlation between MRI-derived and biopsy-confirmed liver iron concentration in patients with
Sari Luthfiyah1, Triwiyanto Triwiyanto2, Luthfi Rusyadi3
1Department of Nursing, Poltekkes Kemenkes Surabaya, Surabaya, Indonesia.
Abstract:
We comment on Ba-Ssalamah et al.'s study comparing MRI-derived and biopsy-confirmed liver iron concentration in chronic liver disease. The strong agreement between two R2*-based methods supports the robustness of relaxometry-based LIC estimation in the low-mild iron range. We discuss physics-related considerations, including R2* nonlinearity, spatial sampling, signal modeling, and calibration dependence, and outline future directions toward volumetric mapping and cross-platform harmonization for quantitative liver MRI.
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