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Updated: Feb 3, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Navigating Infertility and Cardiovascular Risk: Use of Assisted Reproductive Technologies in Women With Heart Disease
Chelsea Williams1, Arya Ardehali1, Sarah Monagle1
1Division of Cardiology, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Assisted reproductive technology (ART) use in women with cardiovascular disease (CVD) is increasing, but its impact on pregnancy outcomes remains understudied. Further research is crucial for managing this vulnerable population.
Area of Science:
- Reproductive Medicine
- Cardiology
- Maternal-Fetal Medicine
Background:
- Assisted reproductive technology (ART) is increasingly used globally for infertility.
- More women with cardiovascular disease (CVD) are seeking ART for pregnancy.
- Limited data exists on ART's impact on pregnancy outcomes in women with pre-existing CVD.
Purpose of the Study:
- To review current literature on ART use in women with CVD.
- To identify knowledge gaps and areas for future research.
- To guide cardiologists in managing CVD patients undergoing ART.
Main Methods:
- Literature review of existing studies on ART and CVD in pregnancy.
- Synthesis of established knowledge and identification of research needs.
Main Results:
- The use of ART in women with CVD is growing.
- There is a significant lack of large-scale studies on ART's effects on pregnancy outcomes in this group.
- Specific risks and optimal management strategies are not well-defined.
Conclusions:
- There is an urgent need for more research into ART's impact on pregnancy outcomes for women with CVD.
- Developing evidence-based guidelines is essential for cardiologists and reproductive specialists.
- Improved understanding will enhance the care of this vulnerable patient population.
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