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Published on: May 27, 2011
Management of an Allogeneic HSCT Recipient with an SICD during and after Total Body Irradiation
Akari Matsuoka1, Shun-Ichi Kimura1, Masakatsu Kawamura1
1Division of Hematology, Jichi Medical University Saitama Medical Center, Japan.
Abstract:
A 19-year-old woman with acute myeloid leukemia who had received a subcutaneous implantable cardioverter defibrillator (SICD) was scheduled to undergo allogeneic hematopoietic stem cell transplantation (HSCT). The conditioning regimen included total body irradiation (TBI) at a dose of 12 Gy, under which the SICD was considered at high risk for malfunction. We planned to deactivate and reactivate the SICD before and after each TBI session to mitigate the risk of device malfunction. Additionally, SICD shielding measures were implemented during TBI to minimize the risk of malfunction. Through these procedures, HSCT could be performed without significant adverse events linked to the SICD.
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